Multiple myeloma (plasma cell myeloma, plasmacytic myeloma, Kahler disease) is a serious plasma cell malignancy, which comes alongwith bone marrow and bone destruction. It accounts for approximately 1% of all types of malignancy and more than 10% of all hematologic malignancies. More than 90% of patients with multiple myeloma develop osteolytic or, to a smaller amount (< 3%), sclerotic bone lesions, known as myeloma bone disease [1, 2].
Br Dr G. Bier